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SV40 large T antigen NLS
CAS No. ——
SV40 large T antigen NLS( —— )
Catalog No. M30528 CAS No. ——
SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. This peptide is generated from Large T antigen residue 47 to 55.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameSV40 large T antigen NLS
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NoteResearch use only, not for human use.
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Brief DescriptionSV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. This peptide is generated from Large T antigen residue 47 to 55.
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DescriptionSV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. This peptide is generated from Large T antigen residue 47 to 55.(In Vitro):SV40 large tumor-antigen (T-ag) nuclear import is enhanced by the protein kinase CK2 (CK2) site (Ser111Ser112) flanking the nuclear localization sequence (NLS). T-ag NLS can enhance nuclear import, despite the fact that PK-C has been shown to inhibit nuclear import of proteins such as lamin B2.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight1401.7
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Molecular FormulaC58H104N20O18S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:Cys-Gly-Gly-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Glu-Asp
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Xiao CY, et al. Negative charge at the protein kinase CK2 site enhances recognition of the SV40 large T-antigen NLS by importin: effect of conformation. FEBS Lett. 1998 Dec 4;440(3):297-301.
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